The "Umbrella Incident" that took place in Raccoon City ended with a missile attack ordered by the government intended to wipe out the deadly zombie virus. Following this catastrophe, the Umbrella Corporation's stock plummeted. This serious blow to the business giant resulted in its complete dissolution. Seven years later, at an airport somewhere in the United States, on an ordinary autumn afternoon, a zombie is unleashed. Now, in an airport beginning to fill with the undead, the horrific disaster is about to repeat itself... Claire Redfield, now a member of an NGO supporting victims of bioterrorism and medical disasters, happens to be in the airport while Leon S. Kennedy comes to the site on a mission to take care of the incident.